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    16800-67-2

    Catalog No. EBD20992

    CAS 16800-67-2

    Name 1H-Indole-1,3-diyl diacetate

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    Basic Information

    Synonyms: indoxyl1,3-diacetate Indoxyl-1,3-diacetate N-Acetylindol-3-ylacetate 1-acetyl-1H-indol-3-ylacetate 1,3-Diacetoxyindole 1H-Indole-1,3-diyldiacetate

    Molecular Formula: C12H11NO4

    Molecular Weight: 233.22

    MDL Number: MFCD00022890

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

    Product Description:
    1-Acetyl-1H-indol-3-yl acetate is an organic compound featuring an indole core structure that is substituted at the nitrogen atom with an acetyl group and at the 3-position with an acetate ester. This specific substitution pattern makes it a valuable and versatile synthetic intermediate, particularly in the field of medicinal chemistry. Its primary application is as a key building block in the synthesis of more complex indole derivatives. The indole scaffold is a privileged structure in drug discovery, found in numerous pharmaceuticals and bioactive molecules. The acetyl group on the nitrogen serves as a common protecting group, while the acetate at the 3-position can be hydrolyzed or further functionalized, allowing for the introduction of various substituents. This compound is therefore instrumental in the research and development of potential drug candidates, especially those targeting neurological or anti-inflammatory pathways where indole-based structures are prevalent. As a specialized heterocyclic intermediate, it is not a commodity chemical but is supplied for research and development purposes. Handling requires standard laboratory precautions for organic compounds.
    Physical Properties

    Boiling Point: 345.3 °C at 760 mmHg

    Flash Point: 162.6 °C

    Density: 1.21 g/cm3

    Storage: −20°C

    Analytical Data

    Appearance: Light brown solid

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