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    164456-75-1

    Catalog No. EBD2215781

    CAS 164456-75-1

    Name (R)-1-tert-Butyl 2-methyl piperidine-1,2-dicarboxylate

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    Basic Information

    Molecular Formula: C12H21NO4

    Molecular Weight: 243.3

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-1-tert-Butyl 2-methyl piperidine-1,2-dicarboxylate is a chiral piperidine derivative featuring both a tert-butoxycarbonyl (Boc) protecting group on the nitrogen and a methyl ester on the carboxylic acid. This specific stereochemistry (R-configuration) is crucial for its applications in asymmetric synthesis. This compound serves as a key chiral building block and intermediate in pharmaceutical research and development. The Boc-protected amine and the ester group provide orthogonal handles for further chemical modifications, making it a versatile precursor for constructing complex molecules containing the piperidine scaffold. The piperidine ring is a privileged structure found in numerous bioactive compounds and active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Its primary utility lies in medicinal chemistry for the synthesis of potential drug candidates. The product is typically handled under inert atmosphere and stored at low temperatures to ensure stability.
    Physical Properties
    mg g kg ml l t