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    1640282-31-0

    Catalog No. EBD4058135

    CAS 1640282-31-0

    Name 1-[7-(3,4-dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl]methoxy]-1,4-benzoxazepin-4(5H)-yl]-1-Propanone

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    Basic Information

    Synonyms: I-CBP 112 I-CBP112

    Molecular Formula: C27H36N2O5

    Molecular Weight: 468.59

    Categories: Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    The compound with CAS number 1640282-31-0, known as 1-[7-(3,4-dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl]methoxy]-1,4-benzoxazepin-4(5H)-yl]-1-propanone, is a complex heterocyclic molecule. It is a derivative of a 1,4-benzoxazepine scaffold, incorporating a 3,4-dimethoxyphenyl group and a (S)-1-methyl-3-piperidinylmethoxy substituent. This compound is a key intermediate in the synthesis of novel therapeutic agents targeting the central nervous system. Specifically, it is utilized in the research and development of potent and selective orexin-2 receptor (OX2R) antagonists. Orexin receptors are involved in regulating sleep-wake cycles, and antagonists are being investigated as potential treatments for insomnia and other sleep disorders. The structural complexity, including the chiral center and the benzoxazepine core, is critical for achieving the desired pharmacological profile. As a specialized synthetic building block with a defined biological target, its primary use is confined to pharmaceutical research and development. It is not a commodity chemical or a general-purpose reagent. Handling requires standard laboratory safety precautions for organic compounds of this nature.
    Physical Properties
    mg g kg ml l t