5'-ADP-Na2, CAS No. 16178-48-6

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16178-48-6

Catalog No. EBD2206546

CAS 16178-48-6

Name 5'-ADP-Na2

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Basic Information

Synonyms: Adenosine-5'-diphosphate,disodiumsalt Adenosine-5-diphosphatedisodiumsalt Adenosine-5-diphosphoricacidsodiumsalt 5-ADP-Na2 Adenosine-5'-diphosphatedisodiumsalt adenosine-5'-diphosphatedisodium(ADP) adenosine-5'-diphosphatedisodium disodium5'-O-{[(hydroxyphosphinato)oxy]phosphinato}adenosine 5'-O-[(phosphonatooxy)phosphinato]adenosine [[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-(hydroxy-sodiooxy-phosphoryl)oxy-phosphoryl]oxysodium 5'-Adenosinediphosphatedisodiumsalt 5'-adp-na2 Adenosine5'-(trihydrogendiphosphate),sodiumsalt Adenosine5'-diphosphate,disodiumsalthydrate

Molecular Formula: C10H13N5Na2O10P2

Molecular Weight: 471.16

MDL Number: MFCD00066635

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Medicinal Chemistry > Biochemicals and Life Science Reagents > Vitamins and Coenzymes

Product Description:

Adenosine 5'-diphosphate disodium salt (ADP disodium salt) is a crucial nucleotide involved in cellular energy transfer and metabolism. It consists of an adenine base, a ribose sugar, and two phosphate groups. As the disodium salt, it offers improved solubility and stability for research and industrial applications. Its primary role is as a key intermediate in the ATP-ADP cycle, which is fundamental to cellular bioenergetics. ADP is the product of ATP hydrolysis during energy-consuming processes and is subsequently re-phosphorylated to ATP via oxidative phosphorylation or substrate-level phosphorylation. This makes it an essential reagent in biochemical studies of enzymes like kinases, ATPases, and in metabolic pathway analysis. It is also used in diagnostic kits for clinical research and as a substrate or standard in various life science applications. Beyond its central role in energy metabolism, ADP is a critical signaling molecule. It acts as an agonist for specific P2Y purinergic receptors on platelets, initiating platelet aggregation—a process vital for hemostasis but also implicated in thrombosis. This dual function underscores its importance in both basic biochemical research and applied fields like cardiovascular disease study and diagnostic development.

Physical Properties

Solubility: Soluble in water

Storage: −20°C

Analytical Data

Appearance: White to off-white powder