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    160233-76-1

    Catalog No. EBD2217529

    CAS 160233-76-1

    Name 6-Bromoquinoline-4-carboxylic acid

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    Basic Information

    Synonyms: 6-Bromoquinoline-4-carboxylicacid

    Molecular Formula: C10H6BrNO2

    Molecular Weight: 252.06

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    6-Bromoquinoline-4-carboxylic acid is a heterocyclic aromatic compound featuring a quinoline core substituted with a bromine atom at the 6-position and a carboxylic acid group at the 4-position. It serves as a versatile and valuable synthetic building block in medicinal chemistry and organic synthesis. Its primary application is as a key intermediate in the synthesis of various biologically active molecules, particularly in pharmaceutical research. The bromine atom provides a reactive site for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), while the carboxylic acid allows for further derivatization into amides, esters, or other functional groups. This compound is notably used in the development of potential therapeutic agents, including kinase inhibitors and other small-molecule drugs targeting various diseases. As a bifunctionalized quinoline derivative, it is a crucial precursor for constructing more complex heterocyclic systems. It is commercially available from suppliers specializing in fine chemicals and advanced intermediates for drug discovery.
    Physical Properties

    Boiling Point: 403.1°C at 760 mmHg

    Flash Point: 197.6°C

    Density: 1.732g/cm3

    mg g kg ml l t