(S)-1-BOC-2-PIPERIDINEACETIC ACID, CAS No. 159898-10-9

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159898-10-9

Catalog No. EBD3071823

CAS 159898-10-9

Name (S)-1-BOC-2-PIPERIDINEACETIC ACID

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Basic Information

Synonyms: 2-((s)-1-(tert-butoxycarbonyl)piperidin-2-yl)aceticacid (S)-1-BOC-2-PIPERIDINEACETICACID (S)-N-BOC-2-PIPERIDINEACETICACID (S)-N-BOC-2-CARBOXYMETHYL-PIPERIDINE (S)-BOC-(2-CARBOXYMETHYL)-PIPERIDINE (S)-(1-BOC-PIPERIDIN-2-YL)-ACETICACID (S)-2-CARBOXYMETHYL-PIPERIDINE-1-CARBOXYLICACIDTERT-BUTYLESTER (S)-1-BOC-PIPERIDIN-2-YLACETICACID,(S)-N-BOC-2-CARBOXYMETHYL-PIPERIDINE [(2S)-1-(tert-butoxycarbonyl)piperidin-2-yl]aceticacid

Molecular Formula: C12H21NO4

Molecular Weight: 243.3

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(S)-1-BOC-2-Piperidineacetic acid is a chiral organic compound featuring a piperidine ring substituted with a BOC-protected amine group and an acetic acid moiety at the 2-position. It serves as a versatile and valuable chiral building block in organic synthesis, particularly in the pharmaceutical industry. Its primary application is as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). The chiral piperidine scaffold is a common structural motif found in numerous drugs targeting the central nervous system, cardiovascular diseases, and other therapeutic areas. The presence of both a protected amine and a carboxylic acid group allows for selective functionalization and incorporation into more complex molecular architectures, making it a crucial precursor for medicinal chemistry research and drug development. While its predominant use is in pharmaceutical synthesis, its well-defined structure and functional groups also make it a useful reagent in general asymmetric synthesis and as a starting material for constructing chiral ligands or catalysts.

Physical Properties

Melting Point: 93-97°C

Boiling Point: 373°C at 760 mmHg

Flash Point: 179.4°C

Density: 1.121g/cm3