PARAMETHASONE ACETATE (200 MG), CAS No. 1597-82-6

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1597-82-6

Catalog No. EBD3061452

CAS 1597-82-6

Name PARAMETHASONE ACETATE (200 MG)

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Basic Information

Synonyms: METILAR HALDRONE HALDRATE CORTIDENE SYNTECORT PARAMETHASONEACETATE(200MG) 16-alpha-methyl-6-alpha-fluoro-prednisolone-21-acetate 21-acetyl-6-alpha-fluoro-16-alpha-methylprednisolone 6-alpha-fluoro-16-alpha-methylprednisolone21-acetate paramethasone21-acetate ParamethasoneAcetate (6alpha,8xi,9xi,10xi,11beta,13xi,16alpha)-6-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-ylacetate (6alpha,11beta,16alpha)-6-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-ylacetate DILAR DILLAR STEMEX C12656 ALONDRA

Molecular Formula: C24H31FO6

Molecular Weight: 434.5

Categories: Medicinal Chemistry > APIs and Their Salts > Dermatological Drugs

Product Description:

Paramethasone acetate is a synthetic glucocorticoid corticosteroid. It is the 21-acetate ester derivative of paramethasone. The compound is characterized by the presence of a fluorine atom at the 6α-position and a methyl group at the 16α-position on the steroid nucleus, which are structural modifications designed to enhance its anti-inflammatory potency relative to its mineralocorticoid activity. Its primary application is in medicine as an active pharmaceutical ingredient (API). Paramethasone acetate exhibits potent anti-inflammatory, anti-allergic, and immunosuppressive properties. It has been used in the treatment of various inflammatory and autoimmune conditions, including severe dermatological disorders such as psoriasis, eczema, and contact dermatitis, often formulated in topical creams or ointments. As a corticosteroid, it functions by binding to glucocorticoid receptors, modulating gene expression to inhibit the production of pro-inflammatory mediators. Due to its potency, its use is typically reserved for short-term management of severe symptoms under medical supervision to minimize the risk of systemic side effects associated with prolonged corticosteroid therapy.

Physical Properties

Boiling Point: 584.2 °C at 760 mmHg

Flash Point: 307.1 °C

Density: 1.29 g/cm1.29 g/cm3