(S)-Benzyl 4-isopropyl-2,5-dioxooxazolidine-3-carboxylate, CAS No. 158257-41-1

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158257-41-1

Catalog No. EBD1960428

CAS 158257-41-1

Name (S)-Benzyl 4-isopropyl-2,5-dioxooxazolidine-3-carboxylate

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Basic Information

Synonyms: (S)-Benzyl4-isopropyl-2,5-dioxooxazolidine-3-carboxylate z-l-valinenca valinenca z-vainenca[forvalganciclovir] z-valine,nca (s)-3-(benzyloxycarbonyl)-4-isopropyl-2,5-oxazolidinedione (s)-4-(1-methylethyl)-2,5-dioxo-3-oxazolidinecarboxylicacidphenylmethylester n-cbz-l-valinen-carboxyanhydride Z-Val-nca (S)-benzyl4-isopropyl-2,5-dioxooxazolidine-3-carboxylateZ-Val-NCA benzyl(4S)-2,5-dioxo-4-(propan-2-yl)-1,3-oxazolidine-3-carboxylate benzyl(4S)-2,5-dioxo-4-(propan-2-yl)-1,3-oxazolidine-3-carbox

Molecular Formula: C14H15NO5

Molecular Weight: 277.27

MDL Number: MFCD00274015

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

Product Description:

Z-L-Valine is a protected amino acid derivative where the amino group of L-valine is protected by a benzyloxycarbonyl (Z or Cbz) group. This white to off-white crystalline powder is a fundamental building block in peptide synthesis. The Z group serves as a common amine-protecting strategy, offering stability under various reaction conditions while being readily removable under mild hydrogenolysis or acidic conditions. Its primary application is in the field of solid-phase and solution-phase peptide synthesis. As a key intermediate, it is used to incorporate the L-valine residue into peptide chains during the sequential assembly process. This compound is crucial for the research and development of therapeutic peptides, peptidomimetics, and other bioactive molecules where valine's hydrophobic side chain is required for structure and function. The product is widely utilized in pharmaceutical research for constructing peptide-based drug candidates and in biochemical studies. It is handled as a standard reagent in laboratories specializing in peptide chemistry and medicinal chemistry.

Physical Properties

Boiling Point: 367.988 °C at 760 mmHg

Flash Point: 176.353 °C

Density: 1.294 g/cm3