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    15788-16-6

    Catalog No. EBD17612

    CAS 15788-16-6

    Name 1H-Benzo[d]imidazole-5-carboxylic acid

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    Basic Information

    Synonyms: 1H-Benzo[d]imidazole-5-carboxylicacid 1H-Benzimidazole-5-carboxylicacid OTAVA-BBBB7014211630 BENZOIMIDAZOLE-5-CARBOXYLICACID AURORA9842 AKOSBBS-00000435 5-BENZIMIDAZOLECARBOXYLICACID 1H-BENZOIMIDAZOLE-5-CARBOXYLICACID 1H-benzimidazole-6-carboxylicacid 5-carboxybenzimidazole 5-carboxylicacidbenzimidazole benzimidazole-5-carboxylicacid 1h-benzimadazole-5-carboxylicacid 1h-benzoimidazole-6-carboxylicacid 1h-benzimidazole-5-carboxylicacid(9ci) 3h-benzo[d]imidazole-5-carboxylicacid

    Molecular Formula: C8H6N2O2

    Molecular Weight: 162.15

    MDL Number: MFCD03225617

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    1H-Benzimidazole-5-carboxylic acid is a heterocyclic aromatic compound featuring a benzimidazole core substituted with a carboxylic acid group at the 5-position. It serves as a versatile and crucial building block in medicinal chemistry and organic synthesis. Its primary application is as a key intermediate in the synthesis of various pharmacologically active compounds. The benzimidazole scaffold is a privileged structure in drug discovery, known for its ability to interact with diverse biological targets. This specific carboxylic acid derivative is utilized to construct molecules with potential activity against viruses, parasites, and in other therapeutic areas. The carboxylic acid group allows for further derivatization into amides, esters, or other functional groups, enabling the fine-tuning of drug-like properties. As a bifunctional molecule containing both a heterocyclic core and a reactive carboxyl group, it is also a valuable organic synthesis building block for constructing more complex heterocyclic systems and functional materials.
    Physical Properties

    Melting Point: >300 °C(lit.)

    Boiling Point: 542.5 °C at 760 mmHg

    Flash Point: 281.9 °C

    Density: 1.506 g/cm3

    Analytical Data

    Appearance: green-grey to grey-brown powder

    mg g kg ml l t