(+)-Cloprostenol isopropyl ester is a synthetic prostaglandin analog, specifically a potent agonist of the prostaglandin F2α (PGF2α) receptor. It is the isopropyl ester derivative of cloprostenol, which enhances its lipophilicity and bioavailability. Its primary and well-established application is in veterinary medicine, particularly in animal reproduction management. It is widely used for the synchronization of estrus (heat) and induction of parturition (birth) in livestock, such as cattle and pigs. By mimicking the luteolytic action of natural PGF2α, it causes regression of the corpus luteum, leading to a drop in progesterone levels and the initiation of a new estrous cycle or labor. While its core use is in animal husbandry, cloprostenol and its derivatives have also been investigated in human medical research for potential applications in ophthalmology (e.g., glaucoma treatment) and obstetrics. However, the isopropyl ester form is predominantly associated with veterinary applications.