FMOC-Arg(Pbf)-OH, CAS No. 154445-77-9

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

154445-77-9

Catalog No. EBD44920

CAS 154445-77-9

Name FMOC-Arg(Pbf)-OH

Get Quote

Basic Information

Synonyms: Na-Fmoc-Ng-2,2,4,6,7-pentamethyl-dihydrobenzofuran-5-sulfonyl-L-arginine FMOC-Arg(pbf)-OH (E)-N~5~-(amino{[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]amino}methylidene)-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]ornithine N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N5-{N-[(2,2,4,5,7-pentamethyl-2,3-dihydro-1-benzofuran-6-yl)sulfonyl]carbamimidoyl}-D-ornithine Fmoc-L-Arg(Pbf)-OH FMOC-N-omega-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine Na-Fmoc-Nw-Pbf-L-arginine na-fmoc-ng-(2,2,4,6,7-pentamethyl-*dihydrobenzofu fmoc-ng-pbf-l-arginine fmoc-arg(pbf) fmoc-arginine(pbf)-oh fmoc-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-l-arginine fmoc-l-arginine(pbf) N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N5-{N-[(2,2,4,5,7-pentamethyl-2,

Molecular Formula: C34H40N4O7S

Molecular Weight: 648.77

MDL Number: MFCD00235804

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

FMOC-Arg(Pbf)-OH is a protected derivative of the amino acid arginine, featuring a 9-fluorenylmethoxycarbonyl (Fmoc) group protecting the alpha-amino group and a 2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl (Pbf) group protecting the guanidino side chain. This compound is a standard building block in solid-phase peptide synthesis (SPPS), particularly for the Fmoc/tBu strategy. Its primary application is in the synthesis of peptides and peptidomimetics for pharmaceutical research and development. The orthogonal protecting groups allow for selective deprotection under mild conditions (Fmoc removed by base, Pbf removed by acid), enabling the efficient assembly of complex peptide sequences containing arginine. As a key intermediate, it is widely used to construct bioactive peptides, including those targeting cardiovascular, neurological, and infectious diseases.

Physical Properties

Melting Point: 132°C

Density: 1.37 g/cm3

Storage: −20°C

Analytical Data

Appearance: White or off-white powder