Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    152922-73-1

    Catalog No. EBD46022

    CAS 152922-73-1

    Name Methyl 1-(Mercaptomethyl)cyclopropaneacetate

    Get Quote
    Basic Information

    Synonyms: methyl1-(mercaptomethyl)cyclopropaneacetate metyl1-(mercaptomethyl)cyclopropaneacetate methy1-(mercaptomethyl)cyclopropaneacetate ethyl[1-(mecaptomethyl)cyclopropyl]acetate[formontelukast] cytammethyl2-[1-(mercaptomethyl)cyclopropyl]acetate methyl2-(1-(mercaptomethyl)cyclopropyl)acetate methyl2-[1-(sulfanylmethyl)cyclopropyl]acetate methyl[1-(mercaptomethyl)cyclopropyl]acetate methyl[1-(sulfanylmethyl)cyclopropyl]acetate

    Molecular Formula: C7H12O2S

    Molecular Weight: 160.23

    MDL Number: MFCD09832879

    Categories: Synthetic Chemistry > Organic Building Blocks > Sulfides and Thioethers Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

    Product Description:
    Methyl 1-(mercaptomethyl)cyclopropaneacetate is a specialized organic compound featuring both a cyclopropane ring and a methyl ester group, with a mercaptomethyl substituent attached to the cyclopropane core. This structure makes it a valuable bifunctional building block in synthetic organic chemistry. Its primary utility lies in its role as a versatile synthetic intermediate. The cyclopropane ring is a key structural motif in many bioactive molecules and materials, known for imparting conformational rigidity and metabolic stability. The presence of both a protected thiol (mercaptomethyl) and an ester group allows for diverse chemical transformations. The thiol can be deprotected and used for further functionalization or conjugation, while the ester can be hydrolyzed to the corresponding acid or reduced to an alcohol, enabling the construction of more complex molecular architectures. This compound is particularly relevant in medicinal chemistry research for the synthesis of potential drug candidates, especially those targeting cysteine proteases or requiring thiol-based bioisosteres. It is also employed in materials science for the development of functionalized polymers and ligands. As a research chemical, it is typically handled under inert atmosphere due to the sensitivity of the thiol group to oxidation.
    Physical Properties

    Boiling Point: 208.899 °C at 760 mmHg

    Flash Point: 92.703 °C

    Density: 1.11 g/cm3

    mg g kg ml l t