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    15224-11-0

    Catalog No. EBD3585217

    CAS 15224-11-0

    Name Cyclopropanecarboxylicacid, 2-(hydroxymethyl)-, ethyl ester

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    Basic Information

    Synonyms: Ethyl2-(hydroxymethyl)cyclopropanecarboxylate Cyclopropanecarboxylicacid,2-(hydroxymethyl)-,ethylester 2-HYDROXYMETHYL-CYCLOPROPANECARBOXYLICACIDETHYLESTER ethyl2‐(hydroxymethyl)cyclopropane‐1‐carboxylate

    Molecular Formula: C7H12O3

    Molecular Weight: 144.17

    Categories: Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates

    Product Description:
    Ethyl 2-(hydroxymethyl)cyclopropanecarboxylate is a versatile organic compound featuring both a cyclopropane ring and two functional groups: an ethyl ester and a hydroxymethyl group. This bifunctional structure makes it a valuable chiral building block in organic synthesis. The cyclopropane moiety is a common structural motif in bioactive molecules, and the presence of two modifiable handles allows for diverse chemical transformations. Its primary application is as a key synthetic intermediate in the preparation of pharmaceutical compounds. For instance, it serves as a crucial precursor in the synthesis of certain antiviral agents and other biologically active molecules that incorporate the strained cyclopropane ring system. The hydroxymethyl group can be oxidized, protected, or further functionalized, while the ester group can be hydrolyzed or reduced, providing multiple pathways for molecular elaboration. As a specialized chiral synthon, it is not a commodity chemical but is used in research and development settings for constructing complex molecular architectures. Standard safety precautions for handling organic compounds should be observed, including the use of personal protective equipment due to its potential irritant properties.
    Physical Properties

    Storage: −20°C

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