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    150-25-4

    Catalog No. EBD18564

    CAS 150-25-4

    Name Bicine

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    Basic Information

    Synonyms: Diethylolglycine N,N-Bis(2-hydroxyethyl)glycine Bicine BICINE=N,N-Bis(2-hydroxyethyl)glycine Bicine,MolecularBiologyGradeN,N-Bis(2-hydroxyethyl)glycine,MolecularBiologyGrade Bicine,ULTROLGrade BICINEbufferSolution BICINE,[N,N-Bis(2-hydroxyethyl)glycine] N,N-Di(2-hydroxyethyl)glycine N,N-Di(2-hydroxyethyl)-glycine N,N-dihydroxyethylglycine di(hydroxyethyl)glycine diethanolglycine [bis-(2-hydroxy-ethyl)-amino]-aceticacid bicinebuffer labotest-bblt00452695 n,n-bis(2-hydroxyethyl)-glycin dheg chelestga

    Molecular Formula: C6H13NO4

    Molecular Weight: 163.17

    MDL Number: MFCD00004295

    Categories: Functional Chemicals > Consumer & Industrial Chemicals > Water Treatment Chemicals Synthetic Chemistry > Basic Synthetic Reagents > Other Basic Synthetic Reagents

    Product Description:
    N,N-Bis(2-hydroxyethyl)glycine, commonly known as bicine, is an organic compound with the chemical formula C6H13NO4. It is a zwitterionic amino acid derivative, specifically a substituted glycine, featuring two hydroxyethyl groups attached to the nitrogen atom. This structure imparts excellent buffering capacity in the physiological pH range. Bicine is primarily utilized as a biological buffer in biochemical and molecular biology applications, particularly in cell culture media and enzyme assays, where it maintains stable pH conditions. Beyond life sciences, it serves as a key component in certain cleaning formulations and acts as a chelating agent in water treatment processes, where it helps control metal ion scaling and corrosion. Its chelating properties are also exploited in some industrial processes. While its primary identity is as a functional buffer and chelant, its molecular structure, containing amine and alcohol functionalities, makes it a potential building block in organic synthesis, though this is not its dominant commercial use. It is generally considered to have low toxicity, aligning with its use in biological systems.
    Physical Properties

    Melting Point: 190 °C (dec.)(lit.)

    Boiling Point: 388.5 °C at 760 mmHg

    Flash Point: 188.8 °C

    Density: 1.05 g/mL at 20 °C

    Solubility: H2O: 1 M at 20 °C, clear, colorless

    Storage: 2-8°C

    Analytical Data

    Appearance: White crystalline powder

    mg g kg ml l t