(3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione, CAS No. 14805-29-9

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14805-29-9

Catalog No. EBD2197446

CAS 14805-29-9

Name (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione

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Basic Information

Synonyms: (3aR,4S,7R,7aS)-4,7-Methano-1H-isoindole-1,3(2H)-dione (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione 4,7-Methano-1H-isoindole-1,3(2H)-dione 4,7-Methano-1H-isoindole-1,3(2H)-dione,hexahydro-,(3aR,4S,7R,7aS)-rel- Bicyclo[2.2.1]hep-tane-2,3-exo-dicarboximide (3Ar,4S,7R,7As)-Rel-Hexahydro-4,7-Methano-1H-Isoindole-1,3(2H)-Dione(Lurasidone) (3aR,4S,7R,7aS)4,7-Methano-1H-isoindole-1,3(2H)-dione (3AR,4S,7R,7AS)-4,7-methano-1H-isoindole-1,3-(2h)-dione (3aR,4S,7R,7aS)-4,7-methano-1H-isoindole-1,3(2H)dione

Molecular Formula: C9H11NO2

Molecular Weight: 165.19

MDL Number: MFCD12964181

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

(3aR,4S,7R,7aS)-4,7-Methano-1H-isoindole-1,3(2H)-dione is a chiral, bicyclic heterocyclic compound featuring a fused isoindole-1,3-dione (phthalimide) structure with a bridging methano group. Its CAS number is 14805-29-9. This compound is characterized by its rigid, three-dimensional scaffold and multiple stereocenters, making it a valuable chiral building block. This compound serves as a key intermediate in the synthesis of complex pharmaceutical molecules. Its rigid, functionalized structure is particularly useful for constructing core frameworks in drug discovery, especially for targets requiring specific three-dimensional shape and chirality. It is employed in the research and development of potential therapeutic agents. As a specialized chiral synthon, it is not a commodity chemical but is utilized in advanced organic synthesis. Its applications are primarily in medicinal chemistry for creating novel active pharmaceutical ingredients (APIs) and in academic research exploring new synthetic methodologies involving constrained heterocycles.

Physical Properties

Boiling Point: 519.7 °C at 760 mmHg

Flash Point: 262.1 °C

Density: 1.55 g/cm3

Analytical Data

Appearance: white