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    147780-39-0

    Catalog No. EBD21533

    CAS 147780-39-0

    Name (S)-2-Amino-6-methoxy-6-oxohexanoic acid hydrochloride

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    Basic Information

    Synonyms: L-2-Aminohexanedioicacid6-methylesterhydrochloride (S)-2-Amino-6-methoxy-6-oxohexanoicacidhydrochloride L-.alpha.-Aminoadipicacid-.delta.-methylester.HCl Hexanedioicacid,2-amino-,6-methylester,(2S)-,hydrochloride(1:1) H-Aad(Ome)-OhHcl

    Molecular Formula: C7H14ClNO4

    Molecular Weight: 211.64

    MDL Number: MFCD01632070

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

    Product Description:
    (S)-2-Amino-6-methoxy-6-oxohexanoic acid hydrochloride is a protected amino acid derivative, specifically the methyl ester hydrochloride salt of (S)-2-aminohexanedioic acid (L-α-aminoadipic acid). It serves as a crucial chiral building block in the synthesis of various biologically active compounds. This compound is primarily utilized in the pharmaceutical industry as a key intermediate for the production of peptide-based drugs and enzyme inhibitors. Its structure, featuring a protected carboxylic acid (methyl ester) and a free α-amino group (as hydrochloride salt), makes it particularly valuable for solid-phase peptide synthesis (SPPS) and the construction of complex molecules targeting specific biological pathways. As a derivative of L-α-aminoadipic acid, it is also relevant in biochemical research related to lysine metabolism and the study of certain metabolic disorders. The compound is typically handled under standard laboratory conditions, and its hydrochloride salt form enhances stability and solubility for synthetic applications.
    Physical Properties

    Boiling Point: 333.3 °C at 760 mmHg

    Flash Point: 155.4 °C

    mg g kg ml l t