(S)-6-Methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-one, CAS No. 147086-79-1

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147086-79-1

Catalog No. EBD503

CAS 147086-79-1

Name (S)-6-Methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-one

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Basic Information

Synonyms: (S)-6-Methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-one 4H-Thieno[2,3-b]thiopyran-4-one,5,6-dihydro-6-methyl-,(6S)- 4H-THIENO[2,3-B]THIOPYRAN-4-ONE (6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-one (6S)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-one Dorzolamidehydrochlorideseventhstep (6s)-5,6-dihydro-6-methyl-4h-thieno(2,3-b)thiopyran-4-one

Molecular Formula: C8H8OS2

Molecular Weight: 184.28

MDL Number: MFCD08273970

Categories: Medicinal Chemistry > APIs and Their Salts > Sensory Drugs Medicinal Chemistry > Drug Impurities and Reference Standards > Impurity Standards

Product Description:

Dorzolamide-2-2, identified by CAS number 147086-79-1, is a key intermediate in the synthesis of Dorzolamide hydrochloride. Dorzolamide hydrochloride is a potent and selective carbonic anhydrase II inhibitor, widely used as an active pharmaceutical ingredient (API) in ophthalmic solutions for the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. As a synthetic intermediate, this compound is crucial in the manufacturing process of the final drug substance. Its precise chemical structure and purity are essential for ensuring the quality, efficacy, and safety of the final pharmaceutical product. Consequently, Dorzolamide-2-2 is also significant as a reference standard or process-related impurity standard in analytical method development and quality control during drug production. The compound's primary relevance lies within the pharmaceutical industry, specifically in the development and production of ophthalmic medications. Its handling requires appropriate safety precautions typical for fine chemical intermediates in a controlled manufacturing environment.

Physical Properties

Boiling Point: 307.5 °C at 760 mmHg

Flash Point: 139.8 °C

Density: 1.300 g/cm3