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    14556-46-8

    Catalog No. EBD3599402

    CAS 14556-46-8

    Name 2-Propanol,1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-

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    Basic Information

    Synonyms: 2-Propanol,1-(tert-butylamino)-3-[(6-chloro-m-tolyl)oxy]-(8CI) (?à)-Bupranolol Bupranol Bupranolol Ophtorenin

    Molecular Formula: C14H22ClNO2

    Molecular Weight: 271.79

    Categories: Medicinal Chemistry > APIs and Their Salts > Cardiovascular Drugs Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

    Product Description:
    Bupranolol is a non-selective beta-adrenergic receptor antagonist (beta-blocker). It is a white to off-white crystalline powder with the chemical formula C14H22ClNO2. Structurally, it is an aryloxypropanolamine derivative, featuring a tert-butylamino group and a chlorine substituent on the aromatic ring. Its primary application is as an active pharmaceutical ingredient (API) in the treatment of cardiovascular diseases, specifically for hypertension (high blood pressure), angina pectoris, and certain cardiac arrhythmias. It works by competitively blocking beta-1 and beta-2 adrenergic receptors, thereby reducing heart rate, myocardial contractility, and cardiac output. It has also been investigated for use in managing anxiety and essential tremor, linking it to neurological applications. Bupranolol is known for its strong and long-lasting beta-blocking activity. It is typically administered orally. As a pharmaceutical substance, it is subject to strict quality control standards regarding purity, identity, and stability for formulation into final drug products.
    Physical Properties

    Boiling Point: 396.3°Cat760mmHg

    Flash Point: 193.5°C

    Density: 1.098g/cm3

    mg g kg ml l t