Fmoc-3-cyclohexyl-D-alanine, CAS No. 144701-25-7

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144701-25-7

Catalog No. EBD1494

CAS 144701-25-7

Name Fmoc-3-cyclohexyl-D-alanine

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Basic Information

Synonyms: fmoc-3-cyclohexyl-D-alanine Fmoc-.beta.-cyclohexyl-D-Ala-OH Fmoc-D-Cha-OH N-alpha-(9-fluorenylmethyloxycarbonyl)-D-cyclohexylalanine 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alanine Fmoc-(R)-3-Cyclohexylalanine n-alpha-fmoc-beta-cyclohexyl-d-alanine n-alpha-(9-fluorenylmethoxycarbonyl)-hexahydro-d-phenylalanine n-alpha-(9-fluorenylmethoxycarbonyl)-d-hexahydrophenylalanine n-alpha-(9-fluorenylmethoxycarbonyl)-beta-cyclohexyl-d-alanine rarechememwb0095 fmoc-beta-cyclohexyl-d-alanine fmoc-beta-cyclohexyl-d-ala-oh

Molecular Formula: C24H27NO4

Molecular Weight: 393.48

MDL Number: MFCD00151912

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

Product Description:

N-Fmoc-3-cyclohexyl-D-alanine is a protected D-amino acid derivative. Its structure features a 9-fluorenylmethoxycarbonyl (Fmoc) group protecting the amine functionality and a cyclohexyl side chain attached to the beta-carbon of the alanine backbone. This configuration makes it a chiral, non-proteinogenic amino acid building block. This compound is a critical reagent in solid-phase peptide synthesis (SPPS) using the Fmoc strategy. The D-configuration and the hydrophobic cyclohexyl side chain are specifically incorporated into synthetic peptides to modulate their biological activity, stability against enzymatic degradation, and conformational properties. It is extensively used in pharmaceutical research for developing peptide-based therapeutics, diagnostic agents, and biochemical probes where enhanced metabolic stability or specific receptor interactions are desired. As a high-purity, specialty chemical, it is supplied for research and development purposes. Handling requires standard precautions for laboratory chemicals, and it should be stored under appropriate conditions to maintain stability.

Physical Properties

Boiling Point: 610.5 °C at 760 mmHg

Flash Point: 323 °C

Density: 1.209 g/cm3

Storage: 2-8°C