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    1440605-51-5

    Catalog No. EBD3331479

    CAS 1440605-51-5

    Name methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S)-1-methyl-4-propylidene-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-Octopyranoside,

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    Basic Information

    Synonyms: 3’,6’-Dehydroclindamycin

    Molecular Formula: C18H31ClN2O5S

    Molecular Weight: 422.97

    Categories: Medicinal Chemistry > Drug Impurities and Reference Standards > Impurity Standards Medicinal Chemistry > APIs and Their Salts > Anti-infectives

    Product Description:
    This compound, with CAS number 1440605-51-5, is a structurally complex molecule identified as a specified impurity of clindamycin hydrochloride. Its systematic name is methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S)-1-methyl-4-propylidene-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-Octopyranoside. It is a derivative of the lincosamide antibiotic clindamycin, featuring modifications including a propylidene group on the pyrrolidine ring. As a designated impurity, its primary application is in the pharmaceutical quality control and analytical testing of clindamycin drug substances and finished products. It serves as a reference standard for the identification, quantification, and monitoring of this specific impurity during the manufacturing process and stability studies, ensuring the safety, efficacy, and compliance of the antibiotic product with regulatory standards (e.g., ICH guidelines, pharmacopoeial monographs). The synthesis and characterization of such impurities are critical for developing and validating sensitive analytical methods, such as HPLC or LC-MS, used in pharmaceutical development and quality assurance. Its availability supports the pharmaceutical industry's commitment to comprehensive impurity profiling and control.
    Physical Properties
    mg g kg ml l t