Boc-L-2-allylglycine dicyclohexylamine salt, CAS No. 143979-15-1

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143979-15-1

Catalog No. EBD45580

CAS 143979-15-1

Name Boc-L-2-allylglycine dicyclohexylamine salt

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Basic Information

Synonyms: boc-l-allylglycine-dcha boc-l-allylglycinedchasalt boc-l-allylglycinedicyclohexylaminesalt boc-l-allylglycinedicyclohexylammoniumsalt boc-algly-ohdcha boc-(allyl)gly-ohdcha Boc-L-Allylglycinedicyclohexylamine (2S)-2-[(tert-butoxycarbonyl)amino]pent-4-enoicacid-N-cyclohexylcyclohexanamine(1:1) N-(tert-butoxycarbonyl)-N-prop-2-en-1-ylglycine Boc-L-Allylglycine.DCHA boc-gly(allyl)-ohdcha (S)-2-(Boc-amino)-4-pentenoicaciddicyclohexylaminesalt Boc-L-2-allylglycinedicyclohexylaminesalt N-(tert-but

Molecular Formula: C22H40N2O4

Molecular Weight: 396.56

MDL Number: MFCD01321013

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

Boc-L-allylglycine dicyclohexylamine salt is a protected amino acid derivative. Its chemical structure features an L-allylglycine core, where the alpha-amino group is protected by a tert-butoxycarbonyl (Boc) group, and the carboxylic acid is present as a dicyclohexylamine (DCHA) salt. This salt form enhances the compound's stability and crystallinity, making it a convenient solid for handling and storage in synthetic workflows. This compound serves as a crucial chiral building block in peptide and peptidomimetic synthesis. The presence of the allyl side chain introduces a versatile handle for further chemical modifications, such as cross-metathesis or radical additions, enabling the construction of complex molecular architectures. It is primarily used in pharmaceutical research for the development of novel therapeutic agents, including enzyme inhibitors and bioactive peptides. The Boc protecting group is readily removable under mild acidic conditions, allowing for sequential peptide chain elongation in solid-phase or solution-phase synthesis. As a specialty amino acid derivative, it is not a commodity chemical but a high-value intermediate for targeted research and development. Its application is firmly rooted in medicinal chemistry and life sciences, distinguishing it from more general-purpose synthetic reagents.

Physical Properties

Boiling Point: 352 °C at 760 mmHg

Flash Point: 166.7 °C

Storage: Store at 0°C