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    1422619-13-3

    Catalog No. EBD3330762

    CAS 1422619-13-3

    Name 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3-hydroxy-5-oxo-, (3R,6E)-6-Heptenoic acid

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    Basic Information

    Molecular Formula: C22H26FN3O6S

    Molecular Weight: 479.52

    Categories: Medicinal Chemistry > Drug Impurities and Reference Standards > Impurity Standards Medicinal Chemistry > APIs and Their Salts > Cardiovascular Drugs

    Product Description:
    This compound, with CAS number 1422619-13-3, is known as Rosuvastatin Impurity Sodium Salt (5-Oxo Rosuvastatin Sodium Salt). It is a sodium salt form of a specified oxidative degradation product of Rosuvastatin, a widely prescribed statin medication. As a defined impurity, its primary and critical application is in the pharmaceutical quality control and analytical development processes for Rosuvastatin. It serves as a certified reference standard (CRS) or impurity standard for method validation, stability studies, and batch release testing to ensure the safety, efficacy, and purity of the active pharmaceutical ingredient (API) and its final dosage forms. Its identification and quantification are essential for regulatory compliance. This impurity standard is crucial for monitoring the degradation profile of Rosuvastatin during manufacturing and storage, helping to establish appropriate specifications and shelf-life for the cardiovascular drug product.
    Physical Properties
    mg g kg ml l t