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    1418130-40-1

    Catalog No. EBD4057608

    CAS 1418130-40-1

    Name 3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

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    Basic Information

    Synonyms: 2-氨基-6-氟苯硼酸频哪醇酯 2-氨基-6-氟苯硼酸频哪醇酯 3-氟-2-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)苯胺

    Molecular Formula: C12H17BFNO2

    Molecular Weight: 237.08

    Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks

    Product Description:
    2-Amino-6-fluorophenylboronic acid pinacol ester is a protected boronic acid derivative. It features an amino group and a fluorine atom on the aromatic ring, with the boronic acid functionality masked as a pinacol ester. This protection enhances its stability, handling, and solubility in organic solvents compared to the free boronic acid. This compound serves as a versatile building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. The presence of both an amino group and a fluorine atom on the phenyl ring makes it a valuable precursor for constructing complex molecules, especially in pharmaceutical research. It is used in the synthesis of various heterocyclic compounds and active pharmaceutical ingredients (APIs), where the fluorine atom can modulate biological activity, lipophilicity, and metabolic stability. As a specialty chemical, it is primarily supplied for research and development purposes. Standard safety precautions for handling organoboron compounds and amines should be observed.
    Physical Properties
    mg g kg ml l t