Ethyl -2-ethoxy-1-[[(2-cyanobiphenyl-4-yl) methyl] benzimidazole] -7-carboxylate, CAS No. 139481-41-7

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

139481-41-7

Catalog No. EBD7341

CAS 139481-41-7

Name Ethyl -2-ethoxy-1-[[(2-cyanobiphenyl-4-yl) methyl] benzimidazole] -7-carboxylate

Get Quote

Basic Information

Synonyms: Ethyl-2-ethoxy-1-[[(2-cyanobiphenyl-4-yl)methyl]benzimidazole]-7-carboxylate Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl)Methyl]Benzimidazole]-7-Carboxylate 1H-benzimidazole-7-carboxylicacid,1-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-,ethyleste ethyl1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate 1H-benzimidazole-7-carboxylicacid,1-[(2'-cyano-[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-,ethylester Ethyl-1-((2'-cyanobiphenyl-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate ethyl-2-ethoxy-1-benzimidazole-7-carboxylate Ethyl2-Ethoxy-1-((2'-Cyanobiphenyl-4-YL)Methyl)-1H-Benzimidazole-7-Carboxylate Ethyl2-ethoxy-1-[(2'-cyanobiphenyl-4-yl)methyl]-1H-benzimidazole-7-carboxylate(C6) Ethyl2-ethoxy-1-[(2'-cyanobiphenyl-4-yl)methyl]-1H-benzimidazole-7-carboxylate Ethyl1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate ethyl-2-ethoxy-1-[[(2'

Molecular Formula: C26H23N3O3

Molecular Weight: 425.48

MDL Number: MFCD09030636

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > APIs and Their Salts > Digestive System Drugs

Product Description:

2-Ethoxy-1-[[(2'-cyanobiphenyl-4-yl)methyl]benzimidazole]-7-carboxylic acid ethyl ester is a key synthetic intermediate in the production of the angiotensin II receptor antagonist (ARB) drug, Telmisartan. Its molecular structure features a benzimidazole core substituted with a biphenyl moiety bearing a nitrile group, which is characteristic of the "sartan" class of antihypertensive agents. This compound is specifically utilized in the final synthetic steps to construct the active pharmaceutical ingredient (API), Telmisartan. Telmisartan is a widely prescribed medication for the treatment of hypertension (high blood pressure) and is also indicated to reduce cardiovascular risk in patients unable to take ACE inhibitors. The intermediate plays a crucial role in forming the specific molecular architecture required for potent and selective antagonism of the angiotensin II type 1 (AT1) receptor. As a specialized benzimidazole derivative, its primary and almost exclusive industrial application is within pharmaceutical synthesis for Telmisartan manufacturing. It is not a commodity chemical or a general-purpose building block, and its handling requires standard precautions for fine chemical intermediates in a controlled laboratory or production environment.

Physical Properties

Boiling Point: 637.542 °C at 760 mmHg

Flash Point: 339.374 °C

Density: 1.19 g/cm3