Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    139399-64-7

    Catalog No. EBD268517

    CAS 139399-64-7

    Name 6-bromo-8-quinolinol

    Get Quote
    Basic Information

    Synonyms: 6-bromo-8-quinolinol 6-bromo-quinolin-8-ol 6-Brom-chinolin-8-ol 6-Brom-8-chinolinol

    Molecular Formula: C9H6BrNO

    Molecular Weight: 224.06

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    6-Bromoquinolin-8-ol is an organic compound featuring a quinoline core substituted with a bromine atom at the 6-position and a hydroxyl group at the 8-position. This bifunctional structure makes it a versatile heterocyclic building block. Its primary application is in pharmaceutical research and development as a key intermediate. The bromine atom serves as a reactive site for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), while the hydroxyl group can be further functionalized or participate in coordination. It is notably used in the synthesis of complex molecules, including potential drug candidates with biological activity, such as kinase inhibitors and antimicrobial agents. Due to its defined reactive handles (bromo and hydroxy), it is also employed as a specialized organic synthesis reagent in academic and industrial laboratories for constructing more elaborate quinoline-based architectures.
    Physical Properties

    Boiling Point: 363.2 °C at 760 mmHg

    Flash Point: 173.5 °C

    Density: 1.705 g/cm3

    mg g kg ml l t