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    139015-32-0

    Catalog No. EBD2203531

    CAS 139015-32-0

    Name (3S)-3-(methylamino)pyrrolidine

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    Basic Information

    Synonyms: (s)-(-)-3-(methylamino)pyrrolidine chempacific38128 (3s)-(-)-3-(methylamino)pyrrolidine (3s)-(-)-3-(methylamino)pyrrolidine95+% 3-(s)-aminopyrroloidine 1-methyl-pyrrolidin-3-ylamine (s)-n-methyl-3-pyrrolidinamine (S)-N-methylpyrrolidin-3-amine (3S)-3-(methylamino)pyrrolidine (3S)-N-methylpyrrolidin-3-amine

    Molecular Formula: C5H12N2

    Molecular Weight: 100.16

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (3S)-(-)-3-(Methylamino)pyrrolidine is a chiral, non-racemic pyrrolidine derivative featuring a secondary amine functional group. It is a versatile and valuable building block in organic synthesis, particularly in the pharmaceutical industry. This compound serves as a key chiral intermediate in the synthesis of various biologically active molecules. Its primary and most significant application is in the production of the blockbuster antiplatelet drug, Clopidogrel (Plavix®). In the synthetic route, it is used to construct the critical stereogenic center of the molecule. Beyond this, its structural motif makes it a useful scaffold for medicinal chemistry, enabling the exploration of new drug candidates targeting a range of therapeutic areas. As a bifunctional molecule containing both a cyclic amine and an exocyclic methylamino group, it offers handles for further chemical modifications. It is typically handled under inert atmosphere due to its amine functionality and sensitivity.
    Physical Properties

    Boiling Point: 164°C

    Flash Point: 31.107 °C

    Density: 0,94 g/cm3

    Refractivity: -20 ° (C=10, EtOH)

    mg g kg ml l t