Cbz-D-homoPhe-OH is a protected amino acid derivative, specifically the N-carboxybenzyl (Cbz) protected form of D-homophenylalanine. Its structure features an extended side chain (homophenylalanine) compared to the natural phenylalanine, with the D-configuration at the chiral center. This compound is a white to off-white crystalline powder. This building block is primarily used in the field of peptide chemistry and pharmaceutical research. The Cbz group serves as a common amine-protecting group that is stable under many reaction conditions but can be selectively removed via catalytic hydrogenation. D-homophenylalanine is a non-natural amino acid used to modify the structure, stability, and biological activity of synthetic peptides. Therefore, Cbz-D-homoPhe-OH is a key intermediate for the solid-phase or solution-phase synthesis of peptide-based drug candidates, enzyme inhibitors, and other bioactive molecules where the incorporation of a D-configured, side-chain-extended aromatic residue is desired. It is handled as a standard laboratory chemical, requiring storage in a cool, dry place. Users should refer to its Safety Data Sheet (SDS) for specific handling and hazard information.