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    1378388-35-2

    Catalog No. EBD4023331

    CAS 1378388-35-2

    Name (2S,4S)-1,2,4-Pyrrolidinetricarboxylic acid 1-(1,1-dimethylethyl) 2-methyl ester

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    Basic Information

    Synonyms: (3S,5S)-1-(叔丁氧基羰基)-5-(甲氧基羰基)吡咯烷-3-羧酸 (3S,5S)-1-(叔丁氧基羰基)-5-(甲氧基羰基)吡咯烷-3-羧酸 (3S,5S)-1-[(叔丁氧基)羰基]-5-(甲氧基羰基)吡咯烷-3-羧酸

    Molecular Formula: C12H19NO6

    Molecular Weight: 273.28

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

    Product Description:
    (3S,5S)-1-(tert-Butoxycarbonyl)-5-(methoxycarbonyl)pyrrolidine-3-carboxylic acid is a chiral, multifunctional pyrrolidine derivative. It features a Boc-protected secondary amine, a methyl ester, and a free carboxylic acid group, making it a versatile building block for organic synthesis. The compound possesses two defined stereocenters in the (3S,5S) configuration. This compound is primarily utilized as a key chiral intermediate in pharmaceutical research and development. Its pyrrolidine scaffold is a common structural motif found in numerous bioactive molecules and active pharmaceutical ingredients (APIs). The presence of orthogonal protecting groups (Boc and methyl ester) and a free acid allows for selective functionalization, enabling its incorporation into more complex target structures, particularly in the synthesis of peptidomimetics and other drug candidates. The specific stereochemistry is crucial for its intended applications, as it is designed to impart desired biological activity or pharmacokinetic properties to the final drug molecule. It is a high-value synthetic intermediate used in the production of specific therapeutic agents, rather than a general-purpose laboratory reagent.
    Physical Properties
    mg g kg ml l t