Amprolium hydrochloride, CAS No. 137-88-2

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137-88-2

Catalog No. EBD48204

CAS 137-88-2

Name Amprolium hydrochloride

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Basic Information

Synonyms: 2-picolinium,1-((4-amino-2-propyl-5-pyrimidinyl)methyl)-,chloride,monohydroc amprol amprol25 amprol25percent mepyrium pyridinium,1-((4-amino-2-propyl-5-pyrimidinyl)methyl)-2-methyl-,chloride,m 5-[(6-methylpyridin-1-yl)methyl]-2-propyl-pyrimidin-4-aminechloridehydrochloride amproliumhcl amproliumhydrochloride 1-(4-amino-2-propylpyrimidin-5-ylmethyl)-2-methylpyridiniumchloridehydrochloride Amprolium HCl 1-([4-Amino-2-propyl-5-pyrimidinyl]methyl)-2-methylpyridiniumchloride

Molecular Formula: C14H20Cl2N4

Molecular Weight: 315.24

MDL Number: MFCD00078831

Categories: Agrochemicals > Animal Health > Endoparasiticides Agrochemicals > Animal Health > Veterinary API

Product Description:

Amprolium hydrochloride is a thiamine (vitamin B1) analog used exclusively as an anticoccidial agent in veterinary medicine. Its chemical structure features a pyrimidine ring substituted with an amino group and an alkyl side chain, which competitively inhibits thiamine uptake by coccidia parasites. This compound is a key active pharmaceutical ingredient (API) in poultry and livestock feed additives and medications. It is primarily administered for the prevention and treatment of coccidiosis, a parasitic disease of the intestinal tract caused by protozoa of the genus *Eimeria*. Amprolium's mechanism of action involves blocking the parasite's ability to utilize thiamine, leading to its death and controlling the infection. As a veterinary drug, it is not used in human medicine. Its application is strictly regulated in animal husbandry to ensure food safety, with established withdrawal periods before treated animals are processed for meat or eggs.

Physical Properties

Solubility: Soluble in water (200 mg/ 4 ml - clear, yellow solution)

Analytical Data

Appearance: white or white-like crystalline powder