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    1358581-37-9

    Catalog No. EBD3330717

    CAS 1358581-37-9

    Name (2S,3R,4S,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)-tetrahydro-6-(hydroxyMethyl)-2-Methoxy-2H-pyran-3,4,5-triol

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    Basic Information

    Synonyms: (2S,3R,4S,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)-tetrahydro-6-(hydroxyMethyl)-2-Methoxy-2H-pyran-3,4,5-triol

    Molecular Formula: C25H27FO6S

    Molecular Weight: 474.54

    Categories: Medicinal Chemistry > APIs and Their Salts > Endocrine & Metabolic Drugs Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    This compound, with the CAS number 1358581-37-9, is a complex organic molecule featuring a glycosyl moiety (tetrahydro-2H-pyran-3,4,5-triol) linked to a substituted biphenyl-thiophene core. It is a key intermediate in the synthesis of Sotagliflozin (also known as LX4211), a dual sodium-glucose co-transporter 1 and 2 (SGLT1/SGLT2) inhibitor. Sotagliflozin is an investigational oral antidiabetic drug developed for the treatment of type 1 and type 2 diabetes. This specific intermediate is crucial in constructing the active pharmaceutical ingredient (API) that works by inhibiting glucose reabsorption in the kidneys and intestines, thereby lowering blood glucose levels. Its synthesis represents a critical step in the manufacturing process of this therapeutic agent. As a high-value synthetic intermediate, it is primarily of interest in pharmaceutical research, development, and production. Handling requires standard laboratory precautions for organic compounds, and its use is strictly within the context of controlled pharmaceutical synthesis.
    Physical Properties
    mg g kg ml l t