tert-Butyl ((2R,3R)-3-(benzyloxy)-1-hydroxybutan-2-yl)carbamate, CAS No. 133565-43-2

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133565-43-2

Catalog No. EBD2219747

CAS 133565-43-2

Name tert-Butyl ((2R,3R)-3-(benzyloxy)-1-hydroxybutan-2-yl)carbamate

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Basic Information

Synonyms: (2R,3R)-2-(Boc-amino)-3-benzyloxy-1-butanol,97% n-t-butoxycarbonyl-o-benzyl-l-threoninol n-boc-l-thr(bzl)-ol n-boc-(2r,3r)-2-amino-3-benzyloxy-1-butanol n-alpha-t-boc-o-benzyl-l-threoninol boc-(2r,3r)-2-amino-3-phenylmethoxy-1-butanol boc-thr(bzl)-ol boc-threoninol(bzl) boc-thr(tbu)-ol tert-Butyl((2R,3R)-3-(benzyloxy)-1-hydroxybutan-2-yl)carbamate Boc-O-Benzyl-D-threoninol (2-BENZYLOXY-1-HYDROXYMETHYL-PROPYL)-CARBAMIDSAURE-TERT-BUTYLESTER N-tert-Butoxycarbonyl-(2S,3S)-2-amino-3-phenylmethoxy-1-butanol N-BOC-D-THR(BZL)-OL-N-BOC-(2S,3S)-2-AMINO-3-BENZYLOXY-1-BUTANOL N-alpha-t-Butyloxycarbonyl-O-benzyl-D-threoninol (2-Benzyloxa-1-hydroxymethyl-propyl)-carbamicacidtert-butylester tert-butyl[(1R,2R)-2-(benzyloxy)-1-(hydroxymethyl)propyl]carbamate tert-butyl[(1S,2S)-2-(benzyloxy)-1-(hydroxymethyl)propyl]carbamate

Molecular Formula: C16H25NO4

Molecular Weight: 295.37

MDL Number: MFCD00235949

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

Product Description:

Tert-Butyl ((2R,3R)-3-(benzyloxy)-1-hydroxybutan-2-yl)carbamate is a chiral organic compound featuring a tert-butoxycarbonyl (Boc) protected amine group, a benzyl-protected hydroxyl group, and a free primary hydroxyl group. Its specific (2R,3R) stereochemistry is a critical structural feature. This compound is primarily utilized as a key chiral building block in the synthesis of complex pharmaceutical agents. Its structure makes it a valuable intermediate for constructing peptide mimetics and other bioactive molecules that require precise stereochemical control. The Boc protecting group is standard in peptide synthesis, allowing for selective deprotection and further coupling reactions. The presence of both protected and free functional groups provides versatility for multi-step synthetic routes, particularly in medicinal chemistry research aimed at developing new therapeutic candidates.

Physical Properties

Boiling Point: 449.023 °C at 760 mmHg

Flash Point: 225.361 °C

Density: 1.089 g/cm3

Storage: Store at 0°C