Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    132118-47-9

    Catalog No. EBD4055778

    CAS 132118-47-9

    Name 7-bromo-2-chloro-3-methylquinoline

    Get Quote
    Basic Information

    Molecular Formula: C10H7BrClN

    Molecular Weight: 256.53

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    7-Bromo-2-chloro-3-methylquinoline is a halogenated quinoline derivative. It serves as a versatile and valuable heterocyclic building block in organic synthesis, particularly in medicinal chemistry. The presence of both bromine and chlorine atoms at different positions on the quinoline core allows for selective functionalization via various cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions. This compound is primarily utilized as a key synthetic intermediate in the research and development of pharmaceutical agents. Its structural motif is found in molecules targeting various biological pathways. For instance, it has been employed in the synthesis of compounds investigated for their potential as kinase inhibitors and other biologically active heterocycles. As a bifunctional halogenated synthon, it is a common starting material for constructing more complex quinoline-based scaffolds. It is typically handled as a solid and requires standard precautions for handling halogenated organic compounds.
    Physical Properties
    mg g kg ml l t