N-[(3R)-3-pyrrolidinyl]acetamide, CAS No. 131900-62-4

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

131900-62-4

Catalog No. EBD2203458

CAS 131900-62-4

Name N-[(3R)-3-pyrrolidinyl]acetamide

Get Quote

Basic Information

Synonyms: (R)-N-(pyrrolidin-3-yl)acetamide N-[(3R)-3-pyrrolidinyl]acetamide r-aap (r)-(+)-3-acetamidopyrrolidine (r)-3-acetamido-pyrrolidine (r)-n-pyrrolidin-3-yl-acetamide (3r)-(+)-3-acetamidopyrrolidine (3r)-(+)-3-acetamidopyrrolidine98+% (r)-3-acetylaminopyrrolidine refdupl:(r)-3-acetamidopyrrolidine 4-(Di-n-butylamino)butyronitrile

Molecular Formula: C6H12N2O

Molecular Weight: 128.17

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(3R)-(+)-3-Acetamidopyrrolidine is a chiral pyrrolidine derivative featuring an acetamido group at the 3-position. It is a versatile chiral building block with a defined (R) configuration. This compound is primarily employed as a key chiral intermediate in the pharmaceutical industry. Its pyrrolidine scaffold is a common structural motif found in numerous bioactive molecules. It has been specifically utilized in the synthesis of potent and selective inhibitors, such as dipeptidyl peptidase IV (DPP-IV) inhibitors for the treatment of type 2 diabetes. The chiral center and functional groups make it valuable for constructing complex drug candidates. As a protected form of a chiral 3-aminopyrrolidine, it serves as a crucial starting material or advanced synthon in medicinal chemistry and asymmetric synthesis. Its utility extends beyond a single application, making it a valuable reagent for exploring structure-activity relationships in drug discovery programs.

Physical Properties

Melting Point: 59°C

Boiling Point: 70-72°C 40mm

Flash Point: 70-72°C/40mm

Density: 1.04 g/cm3

Refractivity: 47 ° (C=1, EtOH)

Storage: Refrigerator