Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    131852-53-4

    Catalog No. EBD13297

    CAS 131852-53-4

    Name (S)-tert-Butyl (1-benzylpyrrolidin-3-yl)carbamate

    Get Quote
    Basic Information

    Synonyms: (S)-tert-Butyl(1-benzylpyrrolidin-3-yl)carbamate tert-butyl(s)-1-benzylpyrrolidin-3-ylcarbamate (s)-1-benzyl-3-(tert-butoxycarbonylamino)pyrrolidine (s)-(-)-1-benzyl-3-(boc-amino)pyrrolidine (s)-1-benzyl-3-(boc-amino)pyrrolidine (s)-n-benzyl-3-boc-aminopyrrolidine (s)-1-benzyl-3-n-boc-amino-pyrrolidine (s)-tert-butyl1-benzylpyrrolidin-3-ylcarbamate (s)-(1-benzyl-pyrrolidin-3-yl)-carbamicacidtert-butylester Tert-Butyl[(3S)-1-Benzylpyrrolidin-3-Yl]Carbamate Tert-Butyl[(

    Molecular Formula: C16H24N2O2

    Molecular Weight: 276.37

    MDL Number: MFCD06762908

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-(-)-1-Benzyl-3-(tert-butoxycarbonylamino)pyrrolidine is a chiral pyrrolidine derivative featuring both a benzyl group and a Boc-protected amino group at the 3-position. This compound serves as a versatile and valuable chiral building block in organic synthesis, particularly in the pharmaceutical industry. Its primary application is as a key chiral intermediate in the synthesis of various active pharmaceutical ingredients (APIs). The Boc-protected amino group allows for selective deprotection and further functionalization, while the chiral pyrrolidine core is a common structural motif found in many biologically active molecules, including enzyme inhibitors and receptor modulators. It is specifically cited in patent literature for the preparation of compounds with potential therapeutic applications. As a chiral amine synthon, it is used to introduce stereochemistry into target molecules, making it crucial for the development of enantiomerically pure drugs. It is typically handled under inert atmosphere and stored at low temperatures to maintain stability.
    Physical Properties

    Melting Point: 77-81 °C(lit.)

    Boiling Point: 385.142 °C at 760 mmHg

    Flash Point: 186.727 °C

    Density: 1.089 g/cm3

    mg g kg ml l t