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    1314999-01-3

    Catalog No. EBD2224059

    CAS 1314999-01-3

    Name (S)-Methyl morpholine-2-carboxylate

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    Basic Information

    Molecular Formula: C6H11NO3

    Molecular Weight: 145.16

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-Methyl morpholine-2-carboxylate is a chiral organic compound featuring a morpholine ring substituted with a methyl ester group at the 2-position. It is a white to off-white solid with the molecular formula C7H13NO3. The (S)-enantiomer is of particular interest in asymmetric synthesis and pharmaceutical development due to its defined stereochemistry. This compound serves as a versatile chiral building block and intermediate in medicinal chemistry. Its primary application is in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates. The morpholine ring is a privileged scaffold found in numerous bioactive molecules, and the ester group provides a handle for further functionalization, such as hydrolysis to the corresponding acid or amide formation. It is specifically cited as a key intermediate in the synthesis of various therapeutic agents. As a bifunctional molecule containing both a secondary amine and an ester, it is a valuable synthon for constructing more complex heterocyclic systems and chiral ligands. Its utility extends beyond specific drug synthesis to general organic synthesis where a chiral, non-racemic morpholine derivative is required.
    Physical Properties
    mg g kg ml l t