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    1289584-82-2

    Catalog No. EBD3734708

    CAS 1289584-82-2

    Name (S)-1-Boc-3-Chloro-pyrrolidine

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    Basic Information

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-1-Boc-3-chloropyrrolidine is a chiral, heterocyclic organic compound featuring a pyrrolidine ring substituted with a chlorine atom at the 3-position and a tert-butoxycarbonyl (Boc) protecting group on the nitrogen atom. The Boc group is a standard amine protecting group in organic synthesis, particularly in peptide chemistry and medicinal chemistry. This compound is primarily utilized as a key chiral building block or intermediate in pharmaceutical research and development. The presence of the chlorine atom provides a reactive handle for further functionalization, while the chiral center (S-configuration) is crucial for constructing biologically active molecules with specific stereochemistry. It is commonly employed in the synthesis of drug candidates, especially those targeting the central nervous system and other therapeutic areas where pyrrolidine-based scaffolds are prevalent. As a versatile synthon, it serves as a precursor to various pharmacologically important structures. Its applications extend beyond pharmaceuticals into general asymmetric synthesis, where it is used to introduce chiral pyrrolidine motifs into more complex molecules.
    Physical Properties
    mg g kg ml l t