Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    1266230-22-1

    Catalog No. EBD2220823

    CAS 1266230-22-1

    Name (R)-7-Fluorochroman-4-amine hydrochloride

    Get Quote
    Basic Information

    Molecular Formula: C9H11ClFNO

    Molecular Weight: 203.64

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

    Product Description:
    (R)-7-Fluorochroman-4-amine hydrochloride is a chiral amine derivative featuring a benzodihydropyran (chroman) core structure with a fluorine substituent at the 7-position. The compound is provided as a hydrochloride salt, enhancing its stability and handling properties for synthetic applications. This compound is primarily utilized as a key chiral building block or intermediate in pharmaceutical research and development. Its structural motif, combining a fluorinated aromatic system with a chiral amine-containing saturated heterocycle, makes it a valuable precursor for the synthesis of biologically active molecules. The specific (R)-enantiomer is often targeted to achieve desired stereochemistry in final drug candidates, particularly in programs focused on central nervous system (CNS) or other therapeutic areas where such scaffolds are explored. As a specialized intermediate, it is typically employed in medicinal chemistry for constructing more complex target structures. Its use underscores the importance of fluorinated and chiral heterocyclic components in modern drug discovery to fine-tune pharmacokinetic and pharmacodynamic properties.
    Physical Properties
    mg g kg ml l t