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    1256359-09-7

    Catalog No. EBD2048955

    CAS 1256359-09-7

    Name 1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

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    Basic Information

    Synonyms: 1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole 1-methyl-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

    Molecular Formula: C14H19BN2O2

    Molecular Weight: 258.12

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters

    Product Description:
    1-Methyl-1H-indazole-6-boronic acid pinacol ester is a heterocyclic boronic ester derivative. It features a 1-methylindazole core structure functionalized with a boronic acid pinacol ester group at the 6-position. This compound is a solid at room temperature and is typically handled under inert conditions due to the sensitivity of the boronic ester moiety. This compound is primarily used as a key synthetic intermediate, particularly in pharmaceutical research and development. The boronic ester group enables it to participate in crucial carbon-carbon bond-forming reactions, most notably the Suzuki-Miyaura cross-coupling reaction. This makes it a valuable building block for constructing complex molecules containing the 1-methylindazole scaffold, which is a privileged structure in medicinal chemistry for targeting various biological pathways. As a specialized boronic ester, its applications are predominantly in the synthesis of potential drug candidates and other bioactive molecules. It is considered a high-value fine chemical for research purposes rather than a bulk commodity.
    Physical Properties
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