(S)-(2-hydroxy-1-(hydroxymethyl)ethyl)carbamic acid tert-butyl ester, CAS No. 125414-41-7

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125414-41-7

Catalog No. EBD235237

CAS 125414-41-7

Name (S)-(2-hydroxy-1-(hydroxymethyl)ethyl)carbamic acid tert-butyl ester

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Basic Information

Synonyms: N-BOC-SERINOL,97 Carbamicacid,[2-hydroxy-1-(hydroxymethyl)ethyl]-,1,1-dimethylethylester tert-butyl[2-hydroxy-1-(hydroxymethyl)ethyl]carbamate (S)-(2-hydroxy-1-(hydroxymethyl)ethyl)carbamicacidtert-butylester 2-((tert-butyloxycarbonyl)amino)-1,3-propanediol tert-butyl(1,3-dihydroxypropan-2-yl)carbamate tert-butyl1,3-dihydroxypropan-2-ylcarbamate 2-(t-butoxycarbonylamino)propane-1,3-diol N-(tert-butoxycarbonyl)-L-serinol N-tert-butyloxycarbonylserinol

Molecular Formula: C8H17NO4

Molecular Weight: 191.22

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

Boc-Serinol, with the CAS number 125414-41-7, is a chemical compound featuring a serine-derived diol structure where the amino group is protected by a tert-butoxycarbonyl (Boc) group. It is a white to off-white crystalline powder. This molecule serves as a versatile chiral building block in organic synthesis and medicinal chemistry. Its primary application is as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research. It is notably used in the preparation of various drug candidates and active pharmaceutical ingredients (APIs). For instance, it has been employed in the synthesis of sphingosine-1-phosphate (S1P) receptor modulators and other bioactive compounds where the serine-derived scaffold is crucial for biological activity. The Boc-protected amino group allows for selective deprotection and further functionalization under mild conditions. As a bifunctional molecule containing both a protected amine and two hydroxyl groups, Boc-Serinol offers multiple points for chemical modification, making it valuable for constructing peptide mimetics, linkers for bioconjugation, and other specialized organic structures. It is commonly handled in research and development laboratories under standard safety protocols for amino acid derivatives.

Physical Properties

Melting Point: 85-89 °C

Boiling Point: 363.022°C at 760 mmHg

Flash Point: 173.35°C

Density: 1.136g/cm3