Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    1240583-48-5

    Catalog No. EBD4011993

    CAS 1240583-48-5

    Name (S)-1-Boc-2-phenylpiperazine

    Get Quote
    Basic Information

    Molecular Formula: C15H22N2O2

    Molecular Weight: 262.35

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-1-Boc-2-phenylpiperazine is a chiral piperazine derivative featuring a tert-butoxycarbonyl (Boc) protecting group on one nitrogen and a phenyl substituent on the other. This compound serves as a crucial chiral building block in medicinal chemistry, particularly for the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Its piperazine core is a privileged scaffold found in numerous bioactive molecules. The primary application of this compound is as a key intermediate in the synthesis of various drug candidates. It has been specifically cited in patent literature and research for the preparation of compounds targeting neurological disorders and other therapeutic areas. The chiral (S)-configuration is essential for imparting specific biological activity in the final drug molecule. The Boc group provides orthogonal protection for the secondary amine, allowing for selective functionalization during multi-step synthetic sequences. As a versatile synthon, it is widely utilized in the construction of complex heterocyclic systems. Its commercial availability in high enantiomeric purity makes it a valuable starting material for both academic research and industrial-scale pharmaceutical production.
    Physical Properties
    mg g kg ml l t