(3S,4S)-3-Aminotetrahydro-2H-pyran-4-ol is a chiral amino alcohol derivative featuring a tetrahydropyran ring system. It is characterized by the presence of both an amino group and a hydroxyl group on adjacent stereocenters, making it a valuable chiral building block. The compound is typically supplied as a hydrochloride salt (e.g., CAS 1240390-32-2) to enhance its stability. This compound serves as a crucial chiral intermediate in pharmaceutical synthesis. Its primary application is in the development of antiviral drugs, particularly as a key fragment for constructing nucleoside analogs and protease inhibitors. The specific stereochemistry of the amino and hydroxyl groups is essential for imparting desired biological activity and selectivity in the final drug molecules. As a bifunctional chiral synthon, it is used in medicinal chemistry to introduce the tetrahydropyran moiety, which is a common structural motif in bioactive compounds. Its synthesis and application are of significant interest in the research and development of new therapeutic agents targeting viral infections.