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    1234356-88-7

    Catalog No. EBD3738464

    CAS 1234356-88-7

    Name (R)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one

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    Basic Information

    Synonyms: (R)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one

    Molecular Formula: C16H13FO

    Molecular Weight: 240.27

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones

    Product Description:
    (R)-4-(2-Fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one is a chiral organic compound featuring a fused tetralone scaffold substituted with a 2-fluorophenyl group at the 4-position. Its molecular formula is C₁₆H₁₃FO, and it is characterized by a specific (R)-configuration at the stereogenic center. This compound is typically a solid at room temperature and is used as a high-purity building block in synthetic chemistry. This chiral tetralone derivative is primarily employed as a key pharmaceutical intermediate in medicinal chemistry research and development. Its structure serves as a core scaffold for constructing more complex molecules, particularly in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas. The presence of the fluorophenyl group and the chiral center is often crucial for imparting desired biological activity and optimizing pharmacokinetic properties in final active pharmaceutical ingredients (APIs). As a specialized chiral synthon, it is not a commodity chemical but is supplied for research purposes. Handling requires standard laboratory precautions for organic compounds. Its main value lies in enabling asymmetric synthesis routes for novel bioactive compounds.
    Physical Properties
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