5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol CAS No.123318-82-1 / Cat No.EBD37492
2-氯-9-(2-去氧-2-氟-bata-D-阿拉伯呋喃)-9H-嘌呤-6-胺
2-氯-9-(2-去氧-2-氟-bata-D-阿拉伯呋喃)-9H-嘌呤-6-胺
氯法拉滨
克罗拉宾
克罗他滨
氯伐他滨
氯法拉宾
克罗拉滨
2-氯-9-(2-去氧-2-氟-β-D-阿拉伯呋喃)-9H-嘌呤-6-胺
(2R,3R,4S,5R)-2-(羟甲基)-4-氟-5-(2-氯-6-氨基-9H-嘌呤-9-基)四氢呋喃-3-醇
(2R,3R,4S,5R)-5-(6-氨基-2-氯-9H-嘌呤-9-基)-4-氟-2-(羟甲基)四氢呋喃-3-醇
Properties
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Appearance:
white solid
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Density:
2.12 g/cm3
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Melting point:
228-2310C
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Boiling point:
550 °C at 760 mmHg
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Flashing point:
286.4 °C
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Storage temperature:
2-8°C
Safety Information
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Symbol:
-
Signal words:
Danger -
Hazard statements:
H300 Fatal if swallowed.
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Precautionary statements:
P264 Wash skin thoroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
NMR Spectrum
Prediction： 1H NMR (300 MHz, d6-DMSO) delta 8.27 (dd, 1H, H8, J=1.8 Hz), 6.33 (dd, J=4.8 Hz, J=13.8 Hz, 1H), 5.95 (d, J=5.1 Hz, 1H), 5.21 (dt, J=4.2 Hz, J=52.8 Hz, 1H), 5.08 (t, J=5.7 Hz, 1H), 4.42 (dq, J=19.1 Hz, 1H), 3.83 (m, J=5.1 Hz, 1H), 3.65 (m, J=6.0 Hz, J=11.7 Hz, 2H)
1H NMR
13C NMR
