5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol CAS No.123318-82-1 / Cat No.EBD37492
clofarabine
5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
2-CHLORO-2'-ARABINOFLUORO-2'-DEOXYADENOSINE
CAFDA
2-chloro-9-(2-deoxy-2-fluoroarabinofuranosyl)adenine
2-chloro-9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-9h-purin-6-amin
2-chloro-9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)adenine
Clolar
2-Chloro-9-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-9H-Purin-6-Amine
2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine
(2R,4R,5R)-5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
(2R,3R,4S,5S)-5-(4-amino-6-chloro-1H-benzo[d]imidazol-1-yl)-4-fluoro-2-(hydroxymethyl)-tetrahydrofuran-3-ol
Properties
-
Appearance:
white solid
-
Density:
2.12 g/cm3
-
Melting point:
228-2310C
-
Boiling point:
550 °C at 760 mmHg
-
Flashing point:
286.4 °C
-
Storage temperature:
2-8°C
Safety Information
-
Symbol:
-
Signal words:
Danger -
Hazard statements:
H300 Fatal if swallowed.
-
Precautionary statements:
P264 Wash skin thoroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
NMR Spectrum
Prediction： 1H NMR (300 MHz, d6-DMSO) delta 8.27 (dd, 1H, H8, J=1.8 Hz), 6.33 (dd, J=4.8 Hz, J=13.8 Hz, 1H), 5.95 (d, J=5.1 Hz, 1H), 5.21 (dt, J=4.2 Hz, J=52.8 Hz, 1H), 5.08 (t, J=5.7 Hz, 1H), 4.42 (dq, J=19.1 Hz, 1H), 3.83 (m, J=5.1 Hz, 1H), 3.65 (m, J=6.0 Hz, J=11.7 Hz, 2H)
1H NMR
13C NMR
