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    1228690-37-6

    Catalog No. EBD3739340

    CAS 1228690-37-6

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    Basic Information

    Molecular Formula: C19H17BrN2O3

    Molecular Weight: 401.26

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    (R)-1-Phenylethyl (5-(4-bromophenyl)-3-methylisoxazol-4-yl)carbamate is a chiral organic compound featuring a 3-methylisoxazole core substituted with a 4-bromophenyl group and a carbamate moiety. The carbamate is further functionalized with a (R)-1-phenylethyl group, introducing a stereogenic center. This specific structural motif, combining a brominated aromatic ring, a heterocyclic isoxazole, and a chiral carbamate, makes it a valuable and specialized building block in medicinal chemistry. Its primary application is as a key synthetic intermediate in pharmaceutical research and development. The presence of the bromine atom offers a versatile handle for further cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), allowing for the introduction of diverse substituents. The chiral carbamate group can serve as a protective group for the amine or be manipulated to explore structure-activity relationships. This compound is particularly relevant in the synthesis of targeted small molecule drug candidates, where such heterocyclic scaffolds are often explored for their biological activity. As a non-commercial, research-grade chemical, it is typically used in laboratory-scale synthesis. Handling requires standard precautions for organic compounds, including the use of personal protective equipment in a well-ventilated fume hood.
    Physical Properties
    mg g kg ml l t