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    1228571-53-6

    Catalog No. EBD2158359

    CAS 1228571-53-6

    Name (R)-2-(1-Aminoethyl)-4-chlorophenol

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    Basic Information

    Synonyms: (R)-2-(1-aMinoethyl)-4-chlorophenol

    Molecular Formula: C8H10ClNO

    Molecular Weight: 171.62

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-2-(1-Aminoethyl)-4-chlorophenol is a chiral aromatic amine derivative featuring a phenol group substituted with a chloro group at the para position and a chiral 1-aminoethyl group at the ortho position. This specific stereochemistry (R-configuration) is crucial for its intended applications. This compound is primarily utilized as a key chiral intermediate in pharmaceutical synthesis. Its structure makes it a valuable building block for constructing more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) where the (R)-enantiomer is required for biological activity or specific pharmacokinetic properties. The presence of both amine and phenol functional groups allows for versatile chemical modifications. As a chiral synthon, it is employed in research and development settings to introduce the chiral 1-phenylethylamine moiety into target structures. Its synthesis and availability support the production of enantiomerically pure drugs, contributing to the fields of medicinal chemistry and asymmetric synthesis.
    Physical Properties
    mg g kg ml l t