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    1227917-52-3

    Catalog No. EBD3170997

    CAS 1227917-52-3

    Name (R)-3-isopropylmorpholine hydrochloride

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    Basic Information

    Synonyms: (R)-3-isopropylmorpholinehydrochloride

    Molecular Formula: C7H16ClNO

    Molecular Weight: 165.66

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-3-Isopropylmorpholine hydrochloride is a chiral amine derivative featuring a morpholine ring substituted with an isopropyl group at the 3-position. It is typically supplied as a hydrochloride salt to enhance its stability and handling properties. The compound is characterized by its specific (R)-configuration, which is crucial for its application in asymmetric synthesis. This compound serves as a key chiral building block and intermediate in pharmaceutical research and development. Its primary application is in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. The morpholine scaffold is a privileged structure in medicinal chemistry, often contributing to improved pharmacokinetic properties and target engagement. The chiral center allows for the construction of enantiomerically pure drug candidates. As a versatile synthetic intermediate, it is used in various organic transformations, including amide bond formation and as a precursor for more complex heterocyclic systems. Its utility extends beyond pharmaceuticals into the preparation of chiral ligands and catalysts.
    Physical Properties
    mg g kg ml l t