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    1227157-98-3

    Catalog No. EBD2220930

    CAS 1227157-98-3

    Name (R)-Pyrrolidin-3-ylmethanol hydrochloride

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    Basic Information

    Synonyms: (R)-Pyrrolidin-3-ylmethanol hydrochloride

    Molecular Formula: C5H12ClNO

    Molecular Weight: 137.61

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-Pyrrolidin-3-ylmethanol hydrochloride is a chiral organic compound featuring a pyrrolidine ring substituted with a hydroxymethyl group at the 3-position. It is typically supplied as a hydrochloride salt to enhance stability and handling. The compound is characterized by its (R)-configuration at the stereogenic center, making it a valuable chiral building block. This compound serves as a crucial intermediate in pharmaceutical research and development. Its primary application lies in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting the central nervous system (CNS). The pyrrolidine scaffold is a privileged structure in medicinal chemistry, and the functionalized hydroxymethyl group provides a versatile handle for further chemical modifications to create diverse molecular libraries. As a bifunctional chiral synthon containing both a secondary amine and a primary alcohol, it is also employed in organic synthesis for constructing complex molecules. Its utility extends to the preparation of ligands for catalysis and other fine chemicals where chirality control is essential.
    Physical Properties
    mg g kg ml l t