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    1217631-74-7

    Catalog No. EBD2321398

    CAS 1217631-74-7

    Name (S)-3-N-Cbz-aminopyrrolidine HCl

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    Basic Information

    Synonyms: benzylN-[(3S)-pyrrolidin-3-yl]carbamatehydrochloride (S)-3-N-Cbz-aminopyrrolidineHCl (S)-benzylpyrrolidin-3-ylcarbamatehydrochloride S-3-CBZ-AMINOPYRROLIDINE-HCl

    Molecular Formula: C12H17ClN2O2

    Molecular Weight: 256.73

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-3-N-Cbz-aminopyrrolidine hydrochloride is a chiral pyrrolidine derivative featuring a benzyloxycarbonyl (Cbz) protected primary amine at the 3-position. This compound is a white to off-white solid and serves as a key chiral building block in organic synthesis, particularly in pharmaceutical research. Its primary application is as a versatile intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The (S)-configured pyrrolidine scaffold is a privileged structure found in numerous biologically active molecules, including protease inhibitors, kinase inhibitors, and other therapeutic agents targeting the central nervous system and metabolic diseases. The Cbz protecting group allows for selective deprotection under mild conditions, facilitating further synthetic elaboration. This compound is commercially available from suppliers specializing in fine chemicals and advanced intermediates for medicinal chemistry. It is typically handled under inert atmosphere and stored in a cool, dry place.
    Physical Properties
    mg g kg ml l t