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    1213103-28-6

    Catalog No. EBD2223113

    CAS 1213103-28-6

    Name (R)-5,7-Difluorochroman-4-amine

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    Basic Information

    Molecular Formula: C9H9F2NO

    Molecular Weight: 185.17

    MDL Number: MFCD07374049

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

    Product Description:
    (R)-5,7-Difluorochroman-4-amine is a chiral amine derivative featuring a benzodihydropyran (chroman) core structure substituted with two fluorine atoms at the 5 and 7 positions. This compound is characterized by its (R)-configuration at the chiral center, making it a valuable building block for the synthesis of enantiomerically pure molecules. This intermediate is primarily utilized in pharmaceutical research and development. It serves as a key chiral precursor in the synthesis of various biologically active compounds. Its structural motif, combining a chroman scaffold with a fluorine-substituted aromatic ring and a chiral amine, is of significant interest in medicinal chemistry for designing molecules with potential therapeutic applications. The presence of fluorine atoms can enhance metabolic stability, lipophilicity, and binding affinity of the final drug candidates. As a specialized chiral intermediate, it is not a commodity chemical but is produced and supplied for targeted synthetic routes in drug discovery programs, particularly those aiming at central nervous system (CNS) or other disease targets.
    Physical Properties
    mg g kg ml l t