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    1212396-52-5

    Catalog No. EBD2224062

    CAS 1212396-52-5

    Name (R)-Morpholine-2-carboxylic acid

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    Basic Information

    Synonyms: (R)-Morpholine-2-carboxylicacid (2R)-Morpholine-2-carboxylicacid (2R)-2-Morpholinecarboxylicacid (2R)-MorpholinecarboxylicacidR-Morpholine-2-carboxylicacid

    Molecular Formula: C5H9NO3

    Molecular Weight: 131.13

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-2-Morpholinecarboxylic acid is a chiral organic compound featuring a morpholine ring substituted with a carboxylic acid group at the 2-position. The presence of the chiral center (R-configuration) makes it a valuable building block for the synthesis of enantiomerically pure compounds. This compound serves as a key chiral intermediate in pharmaceutical research and development. Its primary application is in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly those requiring the introduction of a chiral morpholine moiety. The carboxylic acid group allows for further derivatization through amide bond formation or esterification, enabling its incorporation into larger molecular frameworks. As a bifunctional molecule containing both a secondary amine (within the morpholine ring) and a carboxylic acid, it is also utilized in organic synthesis as a chiral synthon. It finds use in the preparation of ligands, catalysts, and other fine chemicals where stereochemical control is crucial.
    Physical Properties
    mg g kg ml l t